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American Society of Microbiology ABMM Exam Syllabus Topics:
| Section | Weight | Objectives |
|---|---|---|
| Directing Laboratory Testing Functions | 44.5% | - Up-to-date practices, standards, technologies and emerging diseases - Test selection, validation, quality control and interpretation |
| Directing Laboratory Administrative Functions | 19% | - Information management and reporting - Process improvement and risk management - Accreditation, licensure and regulatory requirements - Personnel management, competency assessment and training - Laboratory operations, budgeting and compliance |
| Consulting with Other Medical Professionals | 25% | - Public health, epidemiology and outbreak investigation - Clinical consultation, result interpretation and guidance - Education, research and professional development |
| Ensuring Safety and Security in the Laboratory | 11.5% | - Biological, chemical and physical safety - Security, waste management and emergency response |
American Society of Microbiology ABMM Sample Questions:
A patient with a history of recurrent Clostridioides difficile infection (CDI) is being considered for fecal microbiota transplantation (FMT). Pre-FMT screening of the donor stool sample should include comprehensive testing to exclude potential transmission of enteric pathogens. Which of the following would be the MOST critical to rule out in the donor stool?
- A. Detection of common antibiotic resistance genes not currently expressed.
- B. Quantification of the overall microbial diversity using 16S rRNA gene sequencing.
- C. Presence of non-toxigenic C. difficile strains.
- D. Evidence of asymptomatic carriage of multidrug-resistant organisms (MDROs) such as vancomycin- resistant enterococci (VRE) or carbapenem-resistant Enterobacterales (CRE).
Correct Answer: D 🗳️
A patient with a history of travel to a tropical region presents with cyclical fevers and chills.Peripheral blood smear reveals the presence of merozoites and schizonts within erythrocytes. The absence of crescent-shaped gametocytes makes Plasmodium falciparum less likely. The MOST probable species is:
- A. Plasmodium vivax
- B. Plasmodium knowlesi
- C. Plasmodium malariae
- D. Plasmodium ovale
Correct Answer: A 🗳️
A clinical microbiology laboratory is implementing a new multiplex nucleic acid amplification test (NAAT) for the detection of respiratory viral pathogens. To ensure the quantitative accuracy of the assay, it is essential to include:
- A. External quality assessment samples.
- B. Only positive and negative controls.
- C. Internal controls to monitor for PCR inhibition.
- D. Calibration standards with known concentrations of target nucleic acids.
Correct Answer: D 🗳️
A clinical microbiology laboratory is investigating a cluster of Clostridium difficile infections in a hospital.
Which of the following methods is MOST appropriate for determining if the isolates from different patients are related?
- A. Gram staining and morphology
- B. Molecular typing (e.g., PCR ribotyping)
- C. Enzyme immunoassay for C. difficile toxins
- D. Antimicrobial susceptibility testing
Correct Answer: B 🗳️
An immunocompromised patient develops a disseminated fungal infection. Blood cultures are consistently negative. However, a serum beta-D-glucan assay is markedly elevated. Tissue biopsy reveals the presence of hyaline, septate hyphae with dichotomous branching. The MOST likely causative organism is:
- A. Rhizopus species
- B. Aspergillus fumigatus
- C. Mucor species
- D. Cryptococcus neoformans
Correct Answer: B 🗳️
